People

Directors:

Michael Olivier, Ph.D. Dr. Olivier is the Principal Investigator and Director of the Wisconsin Center of Excellence in Genomics Science (CEGS). He is a Professor in the Department of Physiology at the Medical College of Wisconsin. Dr. Olivier’s research focuses on the analysis of genetic function. He is the component director for National Center for Proteomics Research, an NHLBI-funded mass spectrometry technology development effort at the Biotechnology and Bioengineering Center. He has a long standing record of technology development and implementation in mass spectrometry and in functional genomic analysis. Dr. Olivier manages and coordinates the overall activities of the Center.
 
Lloyd Smith, Ph.D. Dr. Smith is the Co-Director of the Wisconsin Center of Excellence in Genomics Science (CEGS). He is the W. L. Hubbell Professor of Chemistry at the University of Wisconsin in Madison, and his research focuses on the development of powerful new technologies to drive biological research, with particular interest in surface chemistries, mass spectrometry, and the emerging area of synthetic biology. He oversees all aspects of technology development for the CEGS, and coordinates the efforts of all other investigators at UW Madison.

Co-Investigators:

Lisa Cirillo, Ph.D.  Dr. Cirillo is an Associate Professor in the Department of Cell Biology, Neurobiology and Anatomy at the Medical College of Wisconsin. She has considerable experience in the analysis and characterization of transcription factors, chromatin and nucleosome biology.
 
Josh Coon, Ph.D.Dr. Coon is an Associate Professor of Chemistry and Biomolecular Chemistry at UW Madison. His research goals include catalyzing evolution in the rapidly developing field of proteomics and using these technologies to address fundamental problems in developmental biology. He has extensive expertise in ETD ionization for the characterization of protein posttranslational modifications and experience in characterizing histone proteins using mass spectrometry.
 
Steven Duncan, Ph.D. Dr. Duncan is the Marcus Professor of Human and Molecular Genetics and the Director of the Program in Regenerative Medicine in the Department of Cell Biology, Neurobiology and Anatomy at the Medical College of Wisconsin. He is the leading expert in the study of liver gene transcription, and uncovered functional mechanisms by which HNF4, a liver-specific transcription factor, influences liver function and diabetes. His research interests focus on the molecular mechanisms underlying mammalian development and utilize mouse knockout models and embryonic stem cells.
 
Melinda Dwinell, Ph.D. Dr. Dwinell is an Assistant Professor in the Department of Physiology at the Medical College of Wisconsin. She has been involved with the Program for Genomic Applications (PhysGen PGA) at the Medical College of Wisconsin for the past 7 years, and has experience in coordinating training programs and opportunities.
 
Audrey Gasch, Ph.D. Dr. Gasch, is an Assistant Professor of Genetics at UW Madison and a Member of the Genome Center of Wisconsin. Her research focus is investigating the role, regulation and evolution of fungal genomic expression responses to stress, using yeast as a model system.
 
Andrew S. Greene, Ph.D. Dr. Greene is a Professor of Physiology at the Medical College of Wisconsin and the Director of the Biotechnology and Bioengineering Center and of the National Center for Proteomics Research. His research is highly collaborative and spans the areas of molecular and cellular biology, genetics, proteomics, technology development and microcirculatory experiments. Dr. Greene has considerable experience in proteomics, expression analysis and bioinformatics. He also serves as the editor for the journal Physiological Genomics.
 
Jozef Lazar, Ph.D.Dr. Lazar is an Associate Professor in the Dermatology Department and Human and Molecular Genetics Center at the Medical College of Wisconsin. He has considerable experience in physiology, cell and molecular biology, and molecular genetics, including positional cloning, dissection of complex diseases, characterization of gene expression and regulation of gene expression at the transcription level.
 
Shama Mirza, Ph.D.Dr. Mirza is a new Assistant Professor in the Department of Biochemistry at the Medical College of Wisconsin. She is an expert in mass spectrometry, and has developed numerous novel approaches to the quantitative analysis of biological samples using mass spectrometry as a member of the National Center for Proteomics Research.
 
Ronald Stewart, Ph.D. Dr. Stewart is the Bioinformatics Team Leader at the Wisconsin Institutes for Discovery at UW Madison. Dr. Stewart’s areas of expertise include statistics, mathematics, computational biology, information technology, database development and algorithm development.
 
Craig Struble, Ph.D. Dr. Stuble is an Associate Professor in the Department of Mathematics, Statistics, and Computer Science at Marquette University. He is a computer science faculty member with interests in bioinformatics, data mining, artificial intelligence, algorithms, computational algebra, and collaborative computing.
 
Scott Terhune, Ph.D. Dr. Terhune is an Assistant Professor in the Department of Microbiology and Molecular Genetics at the Medical College of Wisconsin. His laboratory is part of the Biotechnology and Bioengineering Center, where he studies protein-protein interactions and protein complexes using mass spectrometry. Dr. Terhune’s research focuses on identifying viral-host protein interactions and the consequences of these interactions during herpesvirus infection.
 

Key Contributors:

Brian Halligan, Ph.D. Dr. Halligan has been instrumental in the development of data analysis tools and protocols for mass spectral data at the National Center for Proteomics Research. He works closely with Dr. Olivier, Dr. Smith, Dr. Greene and other investigators on data analysis related to all aspects of MS analysis.
 
Theresa Lins, M.S. Ms. Lins is the program coordinator for the Wisconsin Center of Excellence in Genomics Science. She has extensive experience in grant writing and program management in the academic, corporate, and non-profit sector.
 
Claudia Olivier, Ph.D. Dr. Olivier has extensive teaching experience at the undergraduate level during her time as an Assistant Professor in the Department of Biological Sciences at the University of Wisconsin-Whitewater. Since joining the Biotechnology and Bioengineering Center at the Medical College of Wisconsin, she has been responsible for the organization and coordination of postdoctoral training efforts as well as career development activities within the Center.

Consultants:

James Thomson, Ph.D. James Thomson is a John D. MacArthur Professor at the University of Wisconsin School of Medicine and Public Health, a faculty member of the Genome Center of Wisconsin, an Adjunct Professor in the Department of Molecular, Cellular, and Developmental Biology at the University of California, Santa Barbara and serves as the Director of Regenerative Biology at the Morgridge Institute for Research. He conducts research in campus laboratories at both the UW and UCSB.