Part of Wisconsin Center of Excellence in Genomics Science moved to San Antonio.
Principal Investigator and Co-director Michael Olivier, Ph.D., recently moved with his group to the Department of Genetics at the Texas Biomedical Research Institute in San Antonio, TX.
While technologies already exist for the genome-wide analysis of gene transcription and DNA methylation, there is a desperate need for new technologies that enable the comprehensive parallel analysis of all protein-DNA interactions (including histones) without prior knowledge or assumptionsSmith, Shortreed, and Olivier, Analyst. 2011 Aug 7; 136(15):3060-5
The regulation of gene transcription is fundamental to the existence of complex multicellular organisms such as humans.Wu et al. PloS One. 2011; 6 (10) :e26217
The GENECAPP strategy employs sequence-specific hybridization capture of a specific DNA fragment to allow the isolation and subsequent characterization of all proteins bound to that region.Wu et al. PloS One. 2011; 6 (10) :e26217
The goal of the Wisconsin Center of Excellence in Genomics Science is to invent novel technologies that will characterize DNA-protein interactions on a genome-wide scale.